Sensitivity to selected contaminants in a biological early warning system using 'Anodonta woodiana' (Mollusca)

Several early warning systems for the monitoring of water quality are based on the assessment of valve opening/closing in bivalves. Tests were conducted to assess the sensitivity of the mussel Anodonta woodiana , installed on the Mosselmonitor, to seven contaminants and evaluate the usefulness of these sensors for detecting pollution events in the Po River (Italy). Mussels were exposed for 30 min to increasing concentrations of chromium (range 0.01–5 mg/L); arsenic (range 0.05–2.5 mg/L); sodium dodecyl sulphate SDS (range 0.25–50 mg/L); phenol (range 0.1–100 mg/L); oxadiazon (range 0.001–5 mg/L); trichloroethylene (range 0.01–100 mg/L); and crude oil (range 0.5–50 mg/L). Treatment with the highest concentration of SDS elicited two types of alarm response. In a second set of tests, the bivalves were exposed for 6 h to a selected concentration of each chemical. Only SDS led to a dramatic alteration of valve opening, resulting in alarms. This system would have limited applications for monitoring drinking water influent. Keywords: bioindication, mussels, valve movement, toxicity test, toxic substance

Thalassaemia intermedia: The role of erythroexchange in the treatment of an indolent wound

Thalassaemia intermedia: the role of erythroexchange in the treatment of an indolent wound

COVID-19 and Blood Groups: A Six-Months Observational Study in Ferrara, Italy

The current literature still gives a little information about the relationships between the ABO blood group system and the immune response to the virus or the different disease outcomes. Hypothesizing the presence of a predisposition by some blood groups to COVID-19, we searched for differences between patients towards the different outcomes of disease.We enrolled 330 inpatients with a diagnosis of COVID-19, determining both their ABO blood group system and Rh factor, collecting demographic, clinical and laboratory data. We searched for relationships with COVID-19 outcomes within an observation period of 180 days (Intensification of Care-IoC, Inhospital death, 180-days mortality). The most frequent ABO blood group was A (45.8%); a minor part was represented by group O (38.8%), B (11.5%), AB (3.9%). As for the Rh factor, 86.7% of patients were Rh-positive. There were no significant differences between blood groups and Rh factors as for age, length of hospital stays (LoS), or Charlson Comorbidity Index (CCI), nor we found significant relationships between the ABO groups and COVID-19 outcomes. A significant relation was found between AB group and IoC (p = 0.03) while as for the Rh factor, the patients with Rh factor positive died with less frequency during the stay (p = 0.03). Cox regression analyses showed substantial differences in the survival functions concerning the Rh factors. The Rh factor seems to be involved in the 180-day prognosis. The survival functions of patients with Rh factor positive show, in fact, significantly better curves when compared to those with Rh factor negative